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Perioral dermatitis carries an excellent prognosis and recurrences are rare providing initiating factors are avoided. Most individuals will start to improve within a few weeks of treatment. If perioral dermatitis recurs, a further 6 week course of antibiotics is recommended. The use of a simplified skin care regime, coupled with avoidance of topical corticosteroids and heavy make-up can prevent recurrences. Consider referral to a dermatologist for resistant cases. Prevention, by avoiding strong topical corticosteroids on the face, is the best option.
As a further precaution, in all patients who are candidates for systemic steroids, ascertain the presence or absence of absolute or relative contraindications to steroid therapy (., brittle diabetes mellitus, active tuberculosis or other chronic bacterial or fungal infection, poorly controlled glaucoma, or psychiatric disease). In patients with HIV infection and other forms of immunosuppression, the risk benefit ratio for prednisone therapy should be determined on a case by case basis. Note: Women should be warned that these doses of systemic corticosteroids can cause short-term menstrual irregularities.